Diagnosis of ophthalmia neonatorum.
نویسندگان
چکیده
Ninety consecutively seen babies with eye discharge in the first three weeks of life were examined. Four babies had "sticky eyes" with no evidence of ophthalmia and had uniformly negative cultures and test results for antichlamydial antibody; these babies were excluded. Of the 86 babies with ophthalmia neonatorum, Neisseria gonorrhoeae was isolated from eight, Chlamydia trachomatis from 44, other bacteria alone from 20, and 14 had negative cultures. Three babies with negative cultures had longstanding conjunctivitis and had been treated with chloramphenicol eye ointment; all had antichlamydial IgM antibodies, indicating that the conjunctivitis was chlamydial. Hence the total number of babies whose conjunctivitis was chlamydial was 47. The result of the Gram stained conjunctival smear correlated well with that of culture and final assessment by the microimmunofluorescence test, enabling an immediate presumptive diagnosis to be made of gonococcal, chlamydial, or bacterial conjunctivitis. Prompt and effective treatment of babies was started. Explanation to the mother and contact tracing were carried out when the confirmatory cultures and antibody tests were completed. The Gram stained conjunctival smear is a highly sensitive, specific, and predictive test for the aetiological agent of ophthalmia neonatorum. By virtue of its simplicity and rapidity the test may be useful in developing countries.
منابع مشابه
Prevalence of Ophthalmia Neonatorum in Calabar, South-South Nigeria: A 3-Year Review
Background: Ophthalmia neonatorum (ON) also known as neonatal conjunctivitis is inflammation of the conjunctiva caused by aseptic or septic factors. It commonly affects newborns usually within the first month of life. This study aimed to determine the prevalence and socio-demographic characteristics of ON in Calabar, Nigeria. Methods: We retrieved all the clinical case notes with diagnosis of ...
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ورودعنوان ژورنال:
- British medical journal
دوره 295 6610 شماره
صفحات -
تاریخ انتشار 1987